CompletedNot Applicable

Intermittent Oro-esophageal Tube Feeding in Traumatic Brain Injury Patients

China98 participantsStarted 2024-03-30

Plain-language summary

This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding or the control group with Nasogastric tube feeding for enteral nutrition support, respectively. Nutritional status, complications, decannulation of tracheostomy tubes and level of consciousness on day 1 and day 28 were recorded and compared.

Who can participate

Age range18 Years

SexALL

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Inclusion Criteria: * age ≥ 18 years, meeting the diagnosis of severe Traumatic Brain Injury, confirmed through MRI * score of Glasgow Coma Scale (GCS) \<8; * presence of no contraindication for enteral nutrition; * with stable vital signs and no severe liver or kidney dysfunction, metabolic disorders, cardiovascular diseases, or multiple complications; * informed consent form was obtained from the patients' family members. Exclusion Criteria: * unable to cooperate in completing treatment and assessment due to personal reasons or other disorders; * complicated with other intracranial lesions, such as stroke; * with severe consciousness disorders caused by other diseases.

What they're measuring

Concentration of hemoglobin

Timeframe: day 1 and day 28

Concentration of albumin

Timeframe: day 1 and day 28

Concentration of prealbumin

Timeframe: day 1 and day 28

body mass index

Timeframe: day 1 and day 28

Trial details

NCT IDNCT06328985

SponsorZeng Xi

Sponsor typeOTHER_GOV

Study typeINTERVENTIONAL

Primary completion2025-10-16

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