Role of Active Deresuscitation After Resuscitation: (NCT06326112) | Clinical Trial Compass
UnknownPhase 2
Role of Active Deresuscitation After Resuscitation:
Canada120 participantsStarted 2024-05-01
Plain-language summary
The RADAR-Canada trial is a pilot RCT undertaken to assess the acceptability of, compliance with, and biologic consequences of a deresuscitation protocol designed to expedite the removal of excess interstitial fluid in patients who remain in a positive fluid balance following admission to an intensive care unit (ICU).
Who can participate
Age range
18 Years – 120 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Age 18 years or older
. Mechanically ventilated for \> 48 hours
. Calculated volume accumulation \> 3 liters since ICU admission or pitting edema in at least two sites (arms, legs, or trunk)
. Admitted to ICU for ≤ five days
. Informed consent obtained from patient or alternate decision-maker
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial is in Phase 2 and its recruitment status is listed as unknown — does that mean it's still actively enrolling patients, and is it even an option worth pursuing right now given that uncertainty?
2The trial is testing 'active deresuscitation,' which means deliberately removing excess fluid after resuscitation — can you explain how that process would work for someone in my situation, and what risks come with intentionally reducing fluid levels in a critically ill patient?
3Since this study is measuring whether the deresuscitation protocol is feasible and acceptable rather than proving it saves lives, what does that mean for what I could realistically expect to gain from participating versus just receiving standard fluid management care?
4This trial covers a wide range of serious conditions including sepsis, ARDS, and trauma — given my specific diagnosis, do you think my situation fits closely enough with what this trial is designed for that joining would actually be relevant to my care?
5If I or my family member were enrolled, what would day-to-day participation look like in the ICU — how closely would the fluid balance be monitored, and would joining this study change any other aspects of my treatment plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.