CompletedNot Applicable

The Influence of Anesthetic Technique on Cerebral Oxygenation During Spinal Surgery

Saudi Arabia54 participantsStarted 2024-02-10

Plain-language summary

Postural changes during anesthesia can lead to decreased cerebral blood flow and oxygenation, especially when moving from a supine to a prone position. This is particularly relevant during spinal surgery with controlled hypotension. Cerebral oximetry, monitored in the frontal cortex using an O3 sensor, is a noninvasive and continuous method to investigate the impact of anesthetic techniques on cerebral oxygenation in such scenarios.

Who can participate

Age range18 Years – 68 Years

SexALL

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Inclusion Criteria: * American Society of Anesthesiologists (ASA) Physical Status I and II * Scheduled for elective spinal surgery * Prone position * General anesthesia with controlled hypotension. Exclusion Criteria: * Hypertension * Coronary artery disease * Renal, hepatic, or cerebral insufficiency, * Patients with coagulopathy or receiving drugs affecting coagulation * Grossly anemic * Hypovolemic patients * Chronically diseased and debilitated patients, * Bleeding more than 200 mL * Hemodynamic instability (decrease of 25% of baseline mean arterial pressure \[MAP\] for three minutes) * Patients with significant baseline bradycardia.

What they're measuring

regional cerebral oxygen saturation

Timeframe: up to 24 weeks

Trial details

NCT IDNCT06325462

SponsorPrince Sultan Military Medical City

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-08-12

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