Ro60 Expression in Macrophages in Sjogren's Disease (NCT06324968) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
Ro60 Expression in Macrophages in Sjogren's Disease
France20 participantsStarted 2024-02-09
Plain-language summary
Context: The Ro60 protein associates with YRNAs (or RNYs) to form the RoRNP complex, which regulates RNA surveillance and maturation. It is hypothesized that its impairment by nuclear penetration of the anti-Ro60 autoantibodies, would deregulate the anti-inflammatory response in monocytes/macrophages (Mo/Mp) in patients with Sjögren's disease (SD).
Who can participate
Age range18 Years – 75 Years
SexALL
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