UnknownNot Applicable

Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets

China30 participantsStarted 2023-06-01

Plain-language summary

To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal pockets in the distal of second molars.

Who can participate

Age range

26 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 26-45 years old * Completely or partially impacted mandibular third molar * No evidence of acute inflammation * In good physical status and oral health * Regular attendance at control visits Exclusion Criteria: * pregnancy or lactation * Aggregate systemic pathologies such as diabetes, thyroid disorders, bone metabolism diseases, among others * Patients taking calcium, bisphosphonates, glucocorticoids, or other drugs that can interfere with bone metabolism * Patients with uncontrolled periodontal conditions, endodontic conditions and other oral disorders * Heavy smoke (10 cigarettes/day or more) * The second molar has no contact with the third molar, or the third molar crown has alveolar bone

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Probing pocket depths (PPD)

Timeframe: postoperative 14 days, 3 6 and 12 months

Distal bone wall defect (DBWD)

Timeframe: postoperative 14 days, 3 6 and 12 months

Clinical attachment lose (CAL)

Timeframe: postoperative 14 days, 3 6 and 12 months

Bleeding on probing (BOP)

Timeframe: postoperative 14 days, 3 6 and 12 months

Trial details

NCT IDNCT06318247

SponsorThe Dental Hospital of Zhejiang University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-30

View on ClinicalTrials.gov More Periodontal Pocket trials

Who can participate

Age range

26 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Probing pocket depths (PPD)

Timeframe: postoperative 14 days, 3 6 and 12 months

Distal bone wall defect (DBWD)

Timeframe: postoperative 14 days, 3 6 and 12 months

Clinical attachment lose (CAL)

Timeframe: postoperative 14 days, 3 6 and 12 months

Bleeding on probing (BOP)

Timeframe: postoperative 14 days, 3 6 and 12 months