Is Local Injection of Mesenchymal Stem Cells After Endoscopic Dilation Safe and Does it Improve the Outcome of Intestinal Stricture in Patients With Crohn's Disease?

Inclusion Criteria: * Patient aged ≥ 18 years with Crohn's Disease diagnosed more than 6 months ago * Background treatment, for Crohn's Disease, stable for 4 months * Presence of stricture (whether de novo or anastomotic), meeting the radiological definition of stenosis, i.e. a combination of the following criteria: (1) localized luminal narrowing (reduction of luminal diameter by at least less than 50% compared to adjacent healthy bowel segment), (2) bowel wall thickening (25% increase in wall thickness compared to adjacent unaffected bowel) and pre-stenotic dilation (luminal diameter greater than 3 cm) * Presence of symptomatic stricture with abdominal pain after meals and limitations on the amount or type of food at screening * Presence of a stenosis accessible by ileo-colonoscopy, not passable (i.e. not allowing the passage of the adult ileo-colonoscope), of a length less than 5 cm, eligible for endoscopic dilation * Patient accepting the study protocol and having signed an informed consent * Patient capable of undergoing entero-MRI Exclusion Criteria: * Patient liable for immediate surgery * Patient with intra-abdominal fistula or abscess * Patient with a stenosis not accessible to ileocolonoscopy * Patient presenting ≥ 2 strictures with impossibility of determining which stenosis is "dominant" and responsible for the symptoms (based on dilation in entero-MRI) * Patient with a stenosis longer than 5 cm * Patient with a contraindication to performing an entero-MRI or t…