By InvitationNot Applicable

A Novel Method of Non-Invasive Brain Stimulation (kTMP) to Enhance Motor Function in Chronic Stroke Patients

United States15 participantsStarted 2025-09-15

Plain-language summary

Stroke is a leading cause of disability with many patients suffering chronic motor function impairments that affect their day-to-day activities. The goal of this proposal is to provide a first assessment of the efficacy of an innovative non-invasive brain stimulation system, kTMP, in the treatment of motor impairment following stroke.

Who can participate

Age range18 Years – 75 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Age 18 or older with stable upper limb motor dysfunction caused by a single ischemic and/or hemorrhagic stroke greater than 6 months prior to recruitment
✓. Fugl-Meyer Assessment: Upper Extremity (FMA UE) score 28-60
✓. Motor evoked potentials in a hand muscle when stimulating ipsilesional cortex with suprathreshold single-pulse TMS (MEP+), a proxy of residual corticospinal function.

Exclusion criteria

✕. Participants with cognitive impairment (MoCA \< 20), language impairment that interferes with their ability to adhere to the protocol or to provide informed consent.
✕. Individuals who are pregnant, have uncontrolled medical problems including but not limited to severe cardiovascular and cardiopulmonary disease, severe alcohol or drug abuse within the past year, or major depression.
✕. Contraindications related to non-invasive brain stimulation

What they're measuring

Fugl- Meyer Assessment (Upper Extremity)

Timeframe: 10 months

Trial details

NCT IDNCT06317194

SponsorMagnetic Tides

Sponsor typeINDUSTRY

Study typeINTERVENTIONAL

Primary completion2027-06-30

View on ClinicalTrials.gov More Stroke trials