Safety and Efficacy of Triple and Quadruple Regimens as First Line Therapy for Management of Helicobacter Pylori Infection in Egyptians

Inclusion Criteria: * 1\. Naïve patients 2. adult \>18 years 3. Patients with positive SAT 4. Patients didn't take any antibiotics for the previous 4 weeks or PPI for the previous 2 weeks 5. Patients diagnosed with duodenal ulcers who have H. pylori infection and treated with triple or quadruple regimens for H. pylori Exclusion Criteria: * 1-Patients had any concern with triple or quadruple regimens such as hypersensitivity to any of the drug 2-Pregnancy or lactation 3-Refusal to sign the informed consent.