Safety, Tolerability, and Immunogenicity of Recombinant Meningococcal Group B Vaccine (E.Coli)

Inclusion Criteria: * Age range from 3 months to 50 years old, legal guardian and/or individual can provide legal identification; * The subjects and/or their legal guardians have the ability to understand the research procedures, agree to participate in the study (and/or their legal guardians agree to the child's participation in the study), and sign an informed consent form; * The subjects and/or their legal guardians are able to participate in all planned follow-up visits; * On the day of enrollment, the axillary temperature was less than 37.3 ℃; * Standards for certain groups of people: * Subjects ≥ 2 years old: laboratory test indicators (as specified in the protocol) within the normal range, or those with abnormalities but no clinical significance (evaluated by clinical doctors); * Female participants of childbearing age: Agree to take effective contraceptive measures within 6 months from enrollment to full vaccination. Exclusion Criteria: * Have received any Group B meningococcal vaccine in the past; * A history of invasive diseases caused by meningococcus or gonococci; * Pregnant or lactating women; * Have any history of severe allergies to vaccines or drugs in the past, such as allergic shock, allergic laryngeal edema, allergic purpura, thrombocytopenic purpura; * Suffering from serious heart disease, liver disease, kidney disease, congenital malformations, developmental disorders, and genetic defects (including but not limited to Down syndrome, moderate to severe …