RecruitingNot Applicable

Socioeconomic Determinants of the Chemical Exposome and Its Genotoxic Effects in Children

France140 participantsStarted 2024-01-29

Plain-language summary

PESTIFOL will include children over 8 and under 12 years old of different socioeconomic positions (SEP), mostly living in the region of Pays de la Loire. This approach should enable us to assess the impact of the SEP, and therefore social inequalities, on chemical expositions and DNA damage, and to characterize which (classes/mixture of) pollutants are major source of DNA damage. The study will also address potential effects associated with geographical location on the exposome and its biological consequences.

Who can participate

Age range8 Years – 12 Years

SexALL

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Inclusion Criteria: * Children over 8 and under 12 years old at the time of inclusion * Children in school in class level CE2, CM1 or CM2 * Living in the Pays de La Loire region, at least 80% of the time * Written informed assent and consent obtained from the participant and both parents or legal representative prior to performing any protocol-related procedures. Exclusion Criteria: \- Disorder precluding understanding of trial information or informed assent.

What they're measuring

Describe DNA damage

Timeframe: 4-6 months

Describe DNA damage

Timeframe: 4-6 months

Describe socio-economic characteristics.

Timeframe: 4-6 months

Describe socio-economic characteristics.

Timeframe: 4-6 months

Trial details

NCT IDNCT06314633

SponsorInstitut Cancerologie de l'Ouest

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01

Contact for this trial

Marie ROBERT, MD

+33240679900 Marie.Robert@ico.unicancer.fr

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