The goal of the Australian Genomics of Chronic Allograft Dysfunction (AUSCAD) study is a single centre (Westmead Hospital), prospective, observational study, which enrols patients at time of kidney (or kidney-transplant) transplant and tracks the post transplant course. The AUSCAD study aims to generate new knowledge and improve outcomes following kidney transplantation. The primary aim is to determine whether important outcomes (including chronic rejection and graft loss) are correlated with patterns of allograft reactivity, gene expression and susceptibility profiles.
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Graft failure
Timeframe: Time Frame: At biopsy or during study follow up after biopsy (expected average 60-months)
Allograft rejection
Timeframe: At biopsy or during study follow up after biopsy (expected average 12-months)
Gene profile
Timeframe: At biopsy - based on collected tissue sample