Intraoperative Electroencephalographic Biomarkers of Postoperative Pain
Chile57 participantsStarted 2024-05-01
Plain-language summary
The goal of this study is to explore whether specific intraoperative EEG signals (brain waves or neuronal electrical activity) are associated with the severity of acute postoperative pain.
Who can participate
Age range
18 Years – 60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* American Society of Anesthesiologist Performance Status I or II
* Scheduled for elective laparoscopic abdominal surgery under General Anesthesia
Exclusion Criteria:
* Body Mass Index \> 35 kg/m2
* Past history or suspected difficult airway
* Craniofacial malformations
* Use of regional anesthesia technique during or after the surgery
* Severe arrhythmia or use of a pacemaker device
* Severe neuropsychiatric illness (Mayor depression, bipolar disorder, schizophrenia)
* Regular use of psychoactive drugs
* Any injury in the right hand
* Past history of peripheral neuropathy
* Diabetes Mellitus
* Known lesion in the spinothalamic tract.
* Analgesics used in the past 72 hours
* Known allergy to propofol
* Previous diagnosis of a condition associated with chronic pain (such as fibromyalgia, rheumatoid arthritis, osteoarthritis, migraine)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Maximum Pain in PACU
Timeframe: From PACU Admission to PACU Discharged, an average of 2 hours