UnknownNot Applicable

Filling Key Research Gaps With Clinical Implications in Mansonellosis and Schistosomiasis: a Network Approach

Italy200 participantsStarted 2021-04-14

Plain-language summary

This is an experimental, multicenter, non-profit study promoted by the Department of Infectious and Tropical Diseases of the IRCCS (Istituto di Ricerca e Cura a carattere scientifico) Sacro Cuore Don Calabria of Negrar which aims to evaluate the presence of endosymbiont Wolbachia in circulating microfilariae obtained from biological samples of individuals infected with M .perstans and the presence of infection with hybrid Schistosoma species in the population of Schistosoma eggs isolated from biological samples of patients with active schistosomiasis.

Who can participate

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria: * samples from patients who gave consent to the storage and use for research purposes of their samples. In the case a network centre necessitates a template for the storage and use for research purposes of their samples; * samples collected before any treatment with praziquantel and/or benzimidazole and/or avermectin and/or diethylcarbamazine and/or doxycycline drug; * samples collected and stored in conditions suitable for this study (Annex 2); * known country of birth of the patient or of most likely infection (if different from the country of birth) Exclusion criteria: \- no compliance with at least one of the above-mentioned inclusion criteria.

What they're measuring

Number of M. perstans microfilariae

Timeframe: Baseline

Percentage of M. perstans microfilariae

Timeframe: Baseline

Number of Schistosoma eggs

Timeframe: Baseline

Percentage of Schistosoma eggs

Timeframe: Baseline

Trial details

NCT IDNCT06311344

SponsorIRCCS Sacro Cuore Don Calabria di Negrar

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-03-31

View on ClinicalTrials.gov More Schistosoma Mansoni trials

Plain-language summary

Who can participate

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.