RecruitingNot Applicable

Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design

Italy50 participantsStarted 2023-08-30

Plain-language summary

compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation) with proms at a 2-year follow-up.

Who can participate

Age range45 Years

SexALL

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Inclusion criteria

✓. Patients aged ≥ 45 years
✓. Patients who are candidates for primary cemented total knee replacement based on physical examination and medical history, including diagnosis of severe knee pain and disability due to at least one of the following:

Exclusion criteria

✕. Patients aged \< 45 years;
✕. Patients who have already undergone hip or knee arthroplasty ankle, previous osteotomy, with severe axial deformities or suffering from rheumatoid arthritis, diabetes or neuromuscular diseases. In this way, homogeneity of the investigated cohort will be guaranteed;
✕. Pregnant women. -

What they're measuring

Periprosthetic bone mineral density measurement

Timeframe: at baseline (day 0)

Periprosthetic bone mineral density measurement

Timeframe: 6 months

Periprosthetic bone mineral density measurement

Timeframe: 12 months

Periprosthetic bone mineral density measurement

Timeframe: 24 months

Trial details

NCT IDNCT06309433

SponsorIstituto Ortopedico Rizzoli

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12

View on ClinicalTrials.gov More Periprosthetic Osteolysis trials