UnknownNot Applicable

Seminal Levels of PGK2 and ACRV1 as Predictors of Micro-TESE Results in NOA

64 participantsStarted 2024-04-01

Plain-language summary

* Measurement of PGK2 and ACRV1 levels in the semen of infertile males undergoing testicular sperm extraction (TESE). * Correlate seminal levels of PGK2 and ACRV1 with sperm retrieval results and histopathology analysis of testicular biopsy samples.

Who can participate

Age range18 Years – 45 Years

SexMALE

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Infertile males with normal volume, functional (non-obstructive) azoospermia. * Age: 18-45 years Exclusion Criteria: * Patients with proven obstructive azoospermia. * Cryptorchidism. * Testicular Agenesis and testicular atrophy. * Patient with exposure to gonadal toxins like chemotherapy, radiotherapy, and alkylating agents.

What they're measuring

Know more about the functional role of PGK2 and ACRV1 in the process of spermatogenesis.

Timeframe: 2 years

Detect if PGK2 and/or AVRV1 level can used as predictor for spermatogenesis in infertile men with non-obstructive azoospermia undergoing Testicular Sperm Extraction.

Timeframe: 2 years

Trial details

NCT IDNCT06307639

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-10-01

View on ClinicalTrials.gov More Male Infertility Due to Azoospermia trials