CompletedNot Applicable

Influence of Intraoperative Blood Salvage and Autotransfusion on Tumor Recurrence After Deceased Donor Liver Transplantation

998 participantsStarted 2015-01-01

Plain-language summary

The practice of intraoperative blood salvage and autotransfusion (IBSA) during deceased donor liver transplantation (DDLT) for hepatocellular carcinoma (HCC) can potentially reduce the need for allogeneic blood transfusion. However, implementing IBSA remains debatable due to concerns about its possible detrimental effects on oncologic recurrence. Hence, a nationwide multi-center study was conducted to investigate further the association between IBSA and post-transplant HCC recurrence, including a stratified subgroup analysis.

Who can participate

Age range18 Years – 80 Years

SexALL

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Inclusion Criteria: * adult-to-adult deceased donor liver transplantation for hepatocellular carcinoma Exclusion Criteria: * patients under 18 years of age * presence of extrahepatic metastasis * combined kidney transplantation * reduced-size or split liver transplantation * re-transplantation

What they're measuring

Postoperative recurrence of liver cancer

Timeframe: 2015.1.1-2020.12.31

Trial details

NCT IDNCT06307158

SponsorZhejiang University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2020-12-31

View on ClinicalTrials.gov More Liver Transplant; Complications trials