CompletedNot Applicable

Defining Treatment Outcomes and Genetic Architecture in Idiopathic Toe Walking*

United States65 participantsStarted 2022-01-01

Plain-language summary

To compare and contrast the clinical, gait and parent-reported outcomes following either non-operative (casting) or operative treatment for children with idiopathic toe walking (ITW) and determine whether there are specific genes associated with ITW.

Who can participate

Age range6 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Diagnosis of Idiopathic Toe Walking Persistent (ITWp)
✓. Between the ages of 6-18 years
✓. Passive dorsiflexion dorsiflexion with knee extension between -10 plantar flexion - + 5 degrees of dorsiflexion, DiGiovanni defined an isolated gastrocnemius contracture as maximum passive ankle dorsiflexion as \< 5 degrees with the knee in full extension

Exclusion criteria

✕. Diagnosis of Autism or autism spectrum disorder
✕. Presence of any indicators of trauma, neuromuscular influence or neurogenic influence as identified by using the Toe Walking Tool

What they're measuring

Gait parameters: Velocity

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Gait Parameters:Stride Length (m)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Three dimensional Gait Analysis:Kinematics (degrees)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Dynamic Motor Control Index during Walking (Walk-DMC)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Three dimensional Gait Analysis:Kinetics (nm/kg)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Quantitative Assessment of Toe Walking

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Pediatric Outcomes Data Collection Instrument

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Trial details

NCT IDNCT06305689

SponsorShriners Hospitals for Children

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-12-31

View on ClinicalTrials.gov More Idiopathic Toe Walking trials

Who can participate

Age range6 Years – 18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Diagnosis of Idiopathic Toe Walking Persistent (ITWp)
✓. Between the ages of 6-18 years
✓. Passive dorsiflexion dorsiflexion with knee extension between -10 plantar flexion - + 5 degrees of dorsiflexion, DiGiovanni defined an isolated gastrocnemius contracture as maximum passive ankle dorsiflexion as \< 5 degrees with the knee in full extension

Exclusion criteria

✕. Diagnosis of Autism or autism spectrum disorder
✕. Presence of any indicators of trauma, neuromuscular influence or neurogenic influence as identified by using the Toe Walking Tool

What they're measuring

Gait parameters: Velocity

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Gait Parameters:Stride Length (m)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Three dimensional Gait Analysis:Kinematics (degrees)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Dynamic Motor Control Index during Walking (Walk-DMC)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Three dimensional Gait Analysis:Kinetics (nm/kg)

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Quantitative Assessment of Toe Walking

Timeframe: Baseline, 6 months post intervention, 1 year post intervention

Pediatric Outcomes Data Collection Instrument

Timeframe: Baseline, 6 months post intervention, 1 year post intervention