RecruitingNot Applicable

Prognosis of Disseminated and Cerebral Toxoplasmosis Hospitalized in Intensive Care in the Era of PCR Diagnosis

France200 participantsStarted 2024-08-01

Plain-language summary

Toxoplasmosis is a common infection whose clinical severity can sometimes justify admission to intensive care, especially in immunocompromised patients. This study should make it possible to evaluate the impact of different anti-infective treatment regimens and to highlight clinical-biological and prognostic differences depending on the type of underlying immunosuppression.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Adult patient hospitalized in intensive care * At least 1 organ failure (SOFA\> or =2) * PCR toxoplasmosis on CSF, blood, BAL, or bone marrow positive within 7 days before or after admission to ICU Exclusion Criteria: * Post-mortem diagnosis * Primary outcome not available * Patient living informed and not opposed to the reuse of their data in this research.

What they're measuring

Mortality rate in intensive care.

Timeframe: 11 years

Trial details

NCT IDNCT06305468

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2026-04-01

Contact for this trial

Clara Vigneron, MD

06 33 14 56 50 clara.vigneron@aphp.fr

View on ClinicalTrials.gov More Toxoplasmosis trials