Protocol Optimization in CT for the Quantification of BMD (NCT06305156) | Clinical Trial Compass
CompletedNot Applicable
Protocol Optimization in CT for the Quantification of BMD
Switzerland167 participantsStarted 2024-03-13
Plain-language summary
Bone mineral density is an important measurement to detect osteoporosis.
The goal of this clinical trial is to compare bone mineral density measurements in CT examinations and DXA scans. The main question it aims to answer is:
* How good is the measurement of bone mineral density in the new photon-counting CT in comparison to DXA
* How can we optimize the CT scan for bone mineral density
Participants will undergo:
* Clinically indicated CT scan on day of inclusion
* Study related DXA scan on a separate appointment
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Informed Consent signed by the subject
* Referral to a regular clinically indicated CT examination covering the lumbar area (e.g., Abdomen, Thorax + Abdomen, Neck + Thorax +Abdomen)
* Informed written and oral consent (interpreter present in case of foreign language patients)
* No contraindication to the clinically indicated CT examination
Exclusion Criteria:
* Patients \< 18 years
* Pregnant women
* Vulnerable subjects
* Contraindications to the clinically indicated CT scan
* Multiple Myeloma
* Diffuse bone metastasis
* Fixateur interne in the lumbar spine
* Kyphoplasty in the lumbar spine
* Enterally administrated contrast agent
* Obtaining informed consent is not possible
* Withdrawal of consent orally or in writing
* Inability to follow the procedures of the investigation, e.g., due to language problems, psychological disorders, dementia, etc. of the subject
* Immobility (patients confined to a wheelchair or to bed)
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Bone mineral density CT
Timeframe: Immediately after CT scan of the participant.
2
Bone mineral density Dual-energy x-ray absorptiometry (DXA)
Timeframe: Immediately after DXA scan of the participant.