Protocol Optimization in CT for the Quantification of BMD

Inclusion Criteria: * Informed Consent signed by the subject * Referral to a regular clinically indicated CT examination covering the lumbar area (e.g., Abdomen, Thorax + Abdomen, Neck + Thorax +Abdomen) * Informed written and oral consent (interpreter present in case of foreign language patients) * No contraindication to the clinically indicated CT examination Exclusion Criteria: * Patients \< 18 years * Pregnant women * Vulnerable subjects * Contraindications to the clinically indicated CT scan * Multiple Myeloma * Diffuse bone metastasis * Fixateur interne in the lumbar spine * Kyphoplasty in the lumbar spine * Enterally administrated contrast agent * Obtaining informed consent is not possible * Withdrawal of consent orally or in writing * Inability to follow the procedures of the investigation, e.g., due to language problems, psychological disorders, dementia, etc. of the subject * Immobility (patients confined to a wheelchair or to bed)