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The Link Between Human Cytomegalovirus Gene Expression and Glutamate Level in Migraine;Relation to Vitamin D Deficiency

72 participantsStarted 2024-05

Plain-language summary

1. To correlate serum 25(OH)-vitamin D level with duration, frequency, and severity of migraine headache attacks 2. To evaluate the relationship between the serum level of vitamin D and other indices in patients with migraine. 3. To correlate the serum level of glutamate with gene expression of in migraine

Who can participate

Age range15 Years – 55 Years

SexALL

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Inclusion criteria

✓. Selected patients fulfilled the criteria for diagnosis of migraine headache based on International Classification of Headache Disorders-II (ICHD-II) diagnostic criteria.
✓. The age of the selected patients ranged between 15 and 55 years of both sexes
✓. Able to give informed consent.

Exclusion criteria

✕. presence of neurological disease other than migraine
✕. presence of other chronic medical conditions
✕. Participants in both groups were excluded from the study if they consumed vitamin D supplements in the preceding 3 months (any dose); or if they were taking medications that could affect vitamin D serum level such as glucocorticoids, thiazide diuretics, or statins. 4)patients refuse to participate in the study

What they're measuring

The Link between human cytomegalovirus gene expression and glutamate levels in Migraine :relationship to the Vit D Deficiency

Timeframe: Baseline

Trial details

NCT IDNCT06304948

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-01

Contact for this trial

Ahmed M Omar

01006037604 ao5520904@gmail.com

View on ClinicalTrials.gov More Migraine trials