CompletedPhase 3

Effect of Topically-applied Milrinone or Nitroglycerin on Internal Mammary Artery Free Flow

Syria46 participantsStarted 2022-01-01

Plain-language summary

Forty-six consecutive patients undergoing elective primary coronary artery bypass grafting were enrolled. After the left IMA was harvested, free flow was measured under controlled hemodynamic conditions before any intervention (flow 1) and at a mean of 12.5 minutes after the topical application of one of three agents (milrinone, nitroglycerin or normal saline) on the IMA (flow 2).

Who can participate

SexALL

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Inclusion Criteria: * patients undergoing elective primary coronary artery bypass grafting Exclusion Criteria: * patients who developed ischemic events during surgery

What they're measuring

LIMA free flow

Timeframe: Immediately following harvesting the LIMA and 10 mintues following the topical application of the drug

Trial details

NCT IDNCT06301880

SponsorDamascus University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-01-31

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