CompletedNot Applicable

Lidocaine Injection: A Nove Block Therapy for Stroke-related Dysphagia

China65 participantsStarted 2022-06-21

Plain-language summary

This was a multicenter randomized controlled study. 66 post-stroke patients with pharyngeal dysphagia were randomly allocated to the observation group (n=33) or the control group (n=33). Both groups were provided with comprehensive rehabilitation including routine rehabilitation and swallowing function training. Besides, the observation group additionally underwent the stellate ganglion block (SGB). At admission and after 20-day treatment, Kubota water swallowing test, video fluoroscopic swallowing study (VFSS), and Rosenbek penetration-aspiration scale (PAS) were used to assess swallowing function.

Who can participate

Age range18 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Diagnosed with ischemic stroke according to the diagnostic criteria, with the stroke occurring in the medulla oblongata and diagnosed as bulbar palsy. * Upper Esophageal Sphincter did not open or opened ineffectively, with food residue or aspiration, revealed by Videofluoroscopic Swallow Study. * Age \>18 years. * First-time stroke. * Steady vital signs, * Transferred or admitted to the Department of Rehabilitation Medicine within 15d after onset. Exclusion Criteria: * Allergy to Lidocaine injection or vitamin B12 injection; * Severe cognitive impairment; * Coagulation disorders; * Severe dysfunction of organs including heart, lungs, kidney, liver, etc.; * Complicated with other neurological diseases; * Dysphagia caused by other diseases or reasons.

What they're measuring

Video fluoroscopic swallowing study

Timeframe: day 1 and day 10

Trial details

NCT IDNCT06301737

SponsorMuhammad

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-05-02

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