CompletedPhase 1/2

Effect of Vitamin D Injection on Hypertrophic Scars and Keloids

Egypt35 participantsStarted 2024-02-27

Plain-language summary

Scars and keloids cause patients severe morbidity and psychological distress. Hypertrophic scars rise above the skin but stay within the scar boundaries, while keloids expand. The development of keloids and hypertrophic scars is a consequence of insufficient wound healing. These lesions are distinguished by excessive ECM deposition. Excessive ECM deposition is caused by increased inflammatory and proliferative processes and decreased remodeling activities. These scarring lesions are also linked to genetic and systemic causes

Who can participate

Age range18 Years – 50 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- Age from 12 years to 50 years. Patients with hypertrophic scars and keloids Exclusion Criteria: Age below 12 years and above 50 years. Patients received other treatment modalities for hypertrophic scars and keloids. Systemic and other skin diseases. Patients were already receiving supplemental vitamin D.

What they're measuring

Clinical scoring by Vancouver Scale Score

Timeframe: 3 months

Trial details

NCT IDNCT06301178

SponsorMostafa Bahaa

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-02-20

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