Not Yet RecruitingNot Applicable

Environmental Influence on Mental Illness Via Modifications of Genomes and Metabolomes in Adolescents With Autism

Ireland, Romania, United Kingdom400 participantsStarted 2024-09

Plain-language summary

The aim of the study is to enrich the understanding of the physiological mechanisms that predispose autistic adolescents to mental illness. It will inform a possible pathway and biomarker handprint of mental illness severity and prognosis to formulate a neurobiologically informed personalization strategy that could be applied for selecting appropriate Evidence Based Intervention (EBI) for treating an adolescent formally diagnosed with Autism.

Who can participate

Age range11 Years – 15 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Autistic Adolescents * Must be able to interact verbally * Parental consent and participants must be able and willing to give written informed assent and to comply with the requirements of the study protocol * Must be willing to return for all study visits and wear the study device at home * Must have access to and be able to operate a smartphone. Exclusion Criteria: * Adolescents with severe motor impairments or schizophrenia * Complex medical conditions, which would interfere with ability to take part in the study visits or outcomes. * Intellectual disability, not capable to attend mainstream school

What they're measuring

Symptoms of anxiety

Timeframe: Months 0-6

Symptoms of anxiety

Timeframe: Months 0-6

Symptoms of depression

Timeframe: Months 0-6

Symptoms of depression

Timeframe: Months 0-6

Trial details

NCT IDNCT06299618

SponsorUniversity College Cork

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-05

Contact for this trial

Project Manager

+353(0)21 4205082 enigma@ucc.ie

View on ClinicalTrials.gov More Autism trials