Metabolic Changes in Healthy Subjects with Acute Binge Drink (NCT06298318) | Clinical Trial Compass
CompletedPhase 1
Metabolic Changes in Healthy Subjects with Acute Binge Drink
China40 participantsStarted 2024-04-27
Plain-language summary
The goal of this double-blinded, randomized trial is to investigate the effects of acute binge drinking on liver function, liver fat content, and lipid metabolism in healthy young subjects. The main questions it aims to answer are:
1\. If acute binge drinking could alleviate liver injury and hepatic steatosis.
Who can participate
Age range
18 Years – 30 Years
Sex
MALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. male aged 18-30 years;
. body mass index (BMI) ranging from 18.5 to 28 kg/m²;
. having prior experience with binge drinking or hangovers, as assessed using the Personal Assessment of Maximum Drinking Capacity Survey Questionnaire
Exclusion criteria
. with alcohol intolerance or alcohol dependence;
. with serious health conditions, such as liver, kidney, cardiovascular, or gastrointestinal diseases;
. vegetarians;
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
hepatic function change
Timeframe: day1-2 of each 0 hour and 1hour and 5hours and 12 hours and 24 hours
2
Hepatic fibrosis change
Timeframe: day1-2 of each 0 hour and 1hour and 5 hours and 12 hours and 24 hours
3
Lipid metabolism change
Timeframe: day1-2 and of each 0 hour and 1hour and 5 hours and 12 hours and 24 hours