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Clinical Evaluation of Injectable Alb-PRF in the Management of Intrabony Defect in Stage-III Periodontitis Patients

32 participantsStarted 2024-08-30

Plain-language summary

Clinical Evaluation of Injectable Albumin Platelet Rich Fibrin Versus Platelet Rich Fibrin in the Management of Intra-bony Defect in Stage-III Periodontitis Patients. The goal of this clinical trial is to compare Injectable Albumin Platelet Rich Fibrin Versus Platelet Rich Fibrin in the Management of Intra-bony Defect in Stage-III Periodontitis Patients. The main question aims to answer are: will Albumin Platelet Rich Fibrin (Alb-PRF) as adjunct to minimally invasive surgical technique (MIST) be superior in terms of improvement in clinical parameters compared to the use of PRF with MIST.

Who can participate

Age range18 Years – 60 Years

SexALL

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Inclusion criteria

✓. Stage III periodontitis patient having at least one tooth with 2-wall, 3-wall, or combined 2- to 3-wall intrabony defect ≥3 mm in depth (assessed by bone sounding, radiographic examination) with clinical attachment level (CAL) ≥5mm and probing pocket depth (PPD) ≥6 mm with no defect extending to a root furcation area.
✓. Vital teeth.
✓. No history of intake of antibiotics or other medications affecting the periodontium in the previous 6 months.
✓. No periodontal therapy carried out in the past 6 months.
✓. Ability to sign an informed consent form.
✓. Patients age ≥18 years old.
✓. Patients who are cooperative, motivated, and hygiene conscious.
✓. Systemically free according to Cornell Medical Index.

Exclusion criteria

✕. Patient undergoing orthodontic treatment.
✕. Pregnant females or breast feeding.
✕. Smokers.
✕. Teeth mobility greater than grade I.

What they're measuring

Clinical attachment level (CAL)

Timeframe: CAL will be measured at base line, 6, and 9 months postoperative

Trial details

NCT IDNCT06297577

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-08-30

Contact for this trial

Mashaal Mohammed, Master

00201094483995 mashaal.abdullah@dentistry.cu.edu.eg

View on ClinicalTrials.gov More Intrabony Periodontal Defect trials