TerminatedNot Applicable

Heat Waves and the Elderly With COPD

Stopped: Study terminated due to recruitment challenges coupled with our focus changing to a different direction.

United States1 participantsStarted 2024-01-01

Plain-language summary

The purpose of this study is to investigate thermoregulatory responses in older individuals with COPD.

Who can participate

Age range

65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 65 years old or older * Diagnosis of COPD Exclusion Criteria: * Known heart disease * Other chronic medical conditions requiring regular medical therapy including cancer, diabetes, uncontrolled hypertension, and uncontrolled hypercholesterolemia etc * Abnormality detected on routine screening suggestive of provokable ischemia or previously undetected cardiac disease or resting left bundle branch block on screening electrocardiogram * Current smokers * Participant with a body mass index ≥31 kg/m2

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Core body temperature

Timeframe: Prior to and throughout each simulated heat wave exposure, an average of 480 minutes

Forced expiratory volume (FEV1)

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each

Forced vital capacity (FVC)

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each

FEV1/FVC ratio

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each

Trial details

NCT IDNCT06295523

SponsorUniversity of Texas Southwestern Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-10-01

View on ClinicalTrials.gov More COPD trials

Who can participate

Age range

65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Core body temperature

Timeframe: Prior to and throughout each simulated heat wave exposure, an average of 480 minutes

Forced expiratory volume (FEV1)

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each

Forced vital capacity (FVC)

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each

FEV1/FVC ratio

Timeframe: Prior to, during, and after each simulated heat wave exposure, approximately 10 min each