CompletedNot Applicable

Toric Intraocular Lens Implantation in Pediatric Cataract

Kazakhstan40 participantsStarted 2024-03-01

Plain-language summary

To evaluate the visual and refractive outcomes after an intraocular lens (IOL) implantation in pediatric eyes with cataract and preexisting corneal astigmatism

Who can participate

Age range

6 Years – 18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Visually significant cataract;
. Corneal astigmatism more than 1.25 diopters;
. Children aged ≥ 6 years and \< 18 years.

Exclusion criteria

. Patients with a corneal diameter less than 9 mm;
. Presence of corneal scarring;
. Irregular astigmatism;
. Intraocular pressure more than 25 mm Hg;
. Active inflammatory process of the eyeball or signs of a previous episode of inflammation;
. Traumatic, subluxated, or complicated cataract;
. Persistent Fetal Vasculature;
. Diseases of the optic nerve or macula that may limit visual potential;

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Uncorrected (UCDVA) and corrected (CDVA) distance visual acuity

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)

Uncorrected (UCNVA) and corrected (CNVA) near visual acuity

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)

Refraction measurements

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)

Trial details

NCT IDNCT06294795

SponsorKazakh Eye Research Institute

Sponsor typeNETWORK

Study typeINTERVENTIONAL

Primary completion2025-02-05

View on ClinicalTrials.gov More Cataract Congenital trials

Who can participate

Age range

6 Years – 18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

. Visually significant cataract;
. Corneal astigmatism more than 1.25 diopters;
. Children aged ≥ 6 years and \< 18 years.

Exclusion criteria

. Patients with a corneal diameter less than 9 mm;
. Presence of corneal scarring;
. Irregular astigmatism;
. Intraocular pressure more than 25 mm Hg;
. Active inflammatory process of the eyeball or signs of a previous episode of inflammation;
. Traumatic, subluxated, or complicated cataract;
. Persistent Fetal Vasculature;
. Diseases of the optic nerve or macula that may limit visual potential;

What they're measuring

Uncorrected (UCDVA) and corrected (CDVA) distance visual acuity

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)

Uncorrected (UCNVA) and corrected (CNVA) near visual acuity

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)

Refraction measurements

Timeframe: recorded at each follow-up (on the fifth day, first month, third month, sixth month, and first year)