Background: Primary malignant melanoma of the esophagus (PMME) is a malignant tumor originating from esophageal melanocytes with a poor prognosis. No international clinical guidelines or tumor staging systems have been proposed for PMME. This study aimed to analyze the clinical characteristics and treatment outcomes of patients with PMME and propose a tumor staging system in PMME. Materials and Methods: The clinical characteristics of 25 patients with PMME at our cancer center were summarized, and 21 patients were enrolled in a pooled analysis with 162 cases (extracted from 74 eligible articles in PubMed) for further survival analysis and proposal of PMME tumor staging.
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Overall Survival(OS)
Timeframe: From date of disease diagnosis until the date of death from any cause, assessed up to 170 months
Disease-free survival (DFS)
Timeframe: From the date of the initial treatments in Sun Yat-sen University Cancer Center to the recurrence of the disease or death due to any cause, assessed up to 170 months