CompletedPhase 1

Molecular Analysis of Intracanal Microbes After Chemomechanical Procedure and Root Canal Medication: A Randomized Controlled Trial

Egypt20 participantsStarted 2022-05-03

Plain-language summary

This study aimed to evaluate clinically the intracanal microbes at molecular level after using established root canal medicament Calcium hydroxide and potential root canal medicament Glycyrrhizin.and Decontamination Analysis of Controls samples.

Who can participate

Age range19 Years – 60 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Single-rooted teeth with a single canal, necrotic pulp (did not respond to sensitivity testing) and symptomatic apical periodontitis * The age ranges from 19 to 60 years Exclusion Criteria:- Receiving antibiotic treatment within the preceding 3 months. * Reporting systemic disease. * Teeth that could not be isolated with rubber dam. * Teeth with periodontal pockets deeper than 3 mm. * Root fracture or badly decayed teeth.

What they're measuring

minimizing of viable bacteria which showed by Real time PCR

Timeframe: after one week

Trial details

NCT IDNCT06291623

SponsorMansoura University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-12-20

View on ClinicalTrials.gov More Bacterial Viability of Necrotic Pulp With Asymptomatic Apical Periodontitis trials