Cannabis use increased 10 fold among adults over the age of 65 between 2014 and 2016 but very little data exists on the extent of their harmful effects on health and behavior. The overarching goal of this project is to test a novel harm reduction strategy in which older individuals who seek to use cannabis for pain, anxiety or mood problems (depression/anxiety) will be randomly assigned to one of three conditions in an 8 week randomized controlled trial: hemp-derived CBD+THC, hemp-derived CBD-THC, or placebo. This work has the ability to directly inform individual choices regarding the use of cannabis products among older adults, and direct policy decisions regulating cannabis formulations on the legal market.
Age range
60 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
Subjective Motor Function
Timeframe: Baseline, 4 weeks, 8 weeks
Balance
Timeframe: Baseline, 4 weeks, 8 weeks
Anxiety
Timeframe: Baseline, 4 weeks, 8 weeks
Depression
Timeframe: Baseline, 4 weeks, 8 weeks
Blood Cytokine Levels
Timeframe: Baseline, 4 weeks, 8 weeks
Depression/Anxiety
Timeframe: Baseline, 4 weeks, 8 weeks
Drug Effects
Timeframe: 4 weeks, 8 weeks
Inhibitory Control
Timeframe: Baseline, 4 weeks, 8 weeks
Cognitive Function
Timeframe: Baseline, 4 weeks, 8 weeks
Pain Intensity and Interference
Timeframe: Baseline, 4 Weeks, 8 Weeks
Cognitive Ability
Timeframe: Baseline, 4 weeks, 8 weeks
Pain Intensity
Timeframe: Baseline, 4 weeks, 8 weeks
Change in Condition
Timeframe: 4 weeks, 8 weeks
Sleep Disturbance
Timeframe: Baseline, 4 weeks, 8 weeks
Sleep-Related Impairment
Timeframe: Baseline, 4 weeks, 8 weeks
Memory
Timeframe: Baseline, 4 weeks, 8 weeks