CompletedNot Applicable

Prognosis in Subacute Ischemic Stroke Using Multimodal Imaging

China28 participantsStarted 2021-02-01

Plain-language summary

We enrolled patients with subacute IS, associated with moderate-to-severe stenosis of the unilateral cervical internal carotid artery, who underwent 4D ASL. Perfusion levels and collateral circulation were compared between groups with favorable prognosis (modified Rankin scale \[mRS\] ≤ 2) and poor prognosis (mRS \> 2).

Who can participate

Age range18 Years – 88 Years

SexALL

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Inclusion criteria

✓. Confirmed unilateral internal carotid artery/MCA atherosclerotic stenosis/occlusion with a stenosis degree \> 50% verified through computed tomography angiography (CTA), magnetic resonance angiography (MRA), or digital subtraction angiography (DSA).
✓. Presence of IS or transient ischemic attack (TIA) symptoms in the circulating blood supply area within the preceding 48 h.
✓. Asymptomatic patients with no history of IS or TIA in the past 6 months.
✓. Performance of 4D ASL tests during hospitalization.

Exclusion criteria

✕. Moderate-to-severe stenosis/occlusion of the contralateral internal carotid artery/middle cerebral arteries.
✕. Age ≤ 18 years old.
✕. Cardioembolic cerebral infarction.
✕. Moyamoya disease.
✕. Combined or previous cerebral hemorrhage or subarachnoid hemorrhage
✕. History of previous cerebral infarction.
✕. Claustrophobia or the presence of intracranial metal implants, cochlear implants, or pacemakers.

What they're measuring

Modified Rankin Scale（mRS） score after 3 months of onset

Timeframe: 3 months

Trial details

NCT IDNCT06289036

SponsorThe First Hospital of Hebei Medical University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-12-31

View on ClinicalTrials.gov More The Levels of Cerebral Perfusion and Collateral Circulation in Patients With Subacute Stroke trials