CompletedNot Applicable

Evaluating the Long-term Effects of Microfocused Ultrasound on Facial Tightening Using Quantitative Instruments

China30 participantsStarted 2023-07-03

Plain-language summary

A non-randomized, evaluator-blinded study was conducted to observe the changes in the face before and after facial rejuvenation using microfocused ultrasound. The efficacy of microfocused ultrasound in facial rejuvenation was evaluated using standardized photographs in conjunction with a dermatological testing system and to explore the effects of microfocused ultrasound on the function of the skin.

Who can participate

Age range25 Years – 60 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Ages between 25 and 60 years old.
✓. Clear manifested skin issues such as sagging and wrinkles: Merz Facial Aesthetics Score of 2 or above.
✓. Absence of significant systemic diseases, cardiovascular disorders, impaired liver or kidney function, malignant tumors, etc.
✓. Willing to participate in this study and sign an informed consent form.

Exclusion criteria

✕. Pregnant or lactating women.
✕. Individuals with a scar-prone constitution, allergic or abnormally healing skin.
✕. Treatment areas with damaged skin, acute inflammation, active infection, rosacea, vitiligo in the progressive stage, or severe acne.
✕. Patients with skin conditions such as urticaria, itching, or other dermatological diseases.
✕. Those with psychological disorders or drug allergies.
✕. Individuals harboring unrealistic expectations about treatment outcomes.
✕. Treatment areas containing metal foreign bodies or fillers deemed unsuitable for treatment by the physician.
✕. Recent facial laser treatments or injections within the past month, including but not limited to filler treatments such as hyaluronic acid, botulinum toxin, and PRP injection therapy.

What they're measuring

Total Volume Change of Nasolabial Folds

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Change in Maximum Depth of Nasolabial Folds

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Vertical Elevation Value of Nasolabial Fold Curve Projection Curve

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Elevation Value of Nasolabial Fold Curve Projection Curve (Along the Nasal Wing Method

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Change in Mid-Facial Volume

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Brow Lift Height

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Trial details

NCT IDNCT06286384

SponsorFirst Affiliated Hospital of Jinan University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-03-10

View on ClinicalTrials.gov More Facial Aging trials

Plain-language summary

Who can participate

Age range25 Years – 60 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

✓. Ages between 25 and 60 years old.
✓. Clear manifested skin issues such as sagging and wrinkles: Merz Facial Aesthetics Score of 2 or above.
✓. Absence of significant systemic diseases, cardiovascular disorders, impaired liver or kidney function, malignant tumors, etc.
✓. Willing to participate in this study and sign an informed consent form.

Exclusion criteria

✕. Pregnant or lactating women.
✕. Individuals with a scar-prone constitution, allergic or abnormally healing skin.
✕. Treatment areas with damaged skin, acute inflammation, active infection, rosacea, vitiligo in the progressive stage, or severe acne.
✕. Patients with skin conditions such as urticaria, itching, or other dermatological diseases.
✕. Those with psychological disorders or drug allergies.
✕. Individuals harboring unrealistic expectations about treatment outcomes.
✕. Treatment areas containing metal foreign bodies or fillers deemed unsuitable for treatment by the physician.
✕. Recent facial laser treatments or injections within the past month, including but not limited to filler treatments such as hyaluronic acid, botulinum toxin, and PRP injection therapy.

What they're measuring

Total Volume Change of Nasolabial Folds

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Change in Maximum Depth of Nasolabial Folds

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Vertical Elevation Value of Nasolabial Fold Curve Projection Curve

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Elevation Value of Nasolabial Fold Curve Projection Curve (Along the Nasal Wing Method

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Change in Mid-Facial Volume

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days

Brow Lift Height

Timeframe: before therapy, immediately post-therapy (within 30 minutes), 7 , 30, 90, 180 ,270,and360days