Transvaginal Detrusor Nerve Radiofrequency Ablation for Treatment of Overactive Bladder

Inclusion Criteria: * Age 21-80 years old, inclusive * Subject is willing to provide Informed Consent, is geographically stable, understands the requirements for completing the bladder diary and is willing to comply with the required diary, follow-up visits, and testing schedules. * Urinary incontinence, predominant urgency incontinence for at least one episode on a 3-days diary. * Reporting at least "moderate bother" on Item 2 on the UDI, "Do you experience a strong feeling of urgency to empty your bladder" (on new patient paperwork) * \>8 micturitions and \>3 urgency episodes per 24 hours on a 3-day bladder diary (see Appendix 2) * 1 UUI episode on a 3-day bladder diary (see Appendix 2) * Not currently taking anti-muscarinic or beta3 agonist therapy (after at least a 2-week wash-out period) * Post-void residual (PVR) ≤ 100 ml NOTE: it may include Subjects with a single PVR of \>100 ml followed by two consecutive PVR measurements of ≤100 ml in the study. We will record the final acceptable PVR measurement in the data. * Ability and willingness to self-catheterize in case this is necessary. * With respect to their reproductive capacity must be post-menopausal or surgically sterile or willing to use a contraceptive method with a failure rate of less than 1% per year when used consistently and correctly from screening until the last follow up Exclusion Criteria: * Pacemaker or internal defibrillator, or any other metallic or electronic implant anywhere in the body. * Any per…