Fatigue and Recovery: a Comparison Between Trail and Marathon (NCT06282341) | Clinical Trial Compass
TerminatedNot Applicable
Fatigue and Recovery: a Comparison Between Trail and Marathon
Stopped: Official premature termination is failure to be included in the marathon group.
France46 participantsStarted 2023-12-28
Plain-language summary
Road marathon is a famous running race known for hundreds of years. Trail running is an emerging running discipline which count new runners every year. Trail running and road marathon are two running endurance disciplines which differed by variation of elevation and nature of the terrain. While marathon is essentially run on flat roads, trail races are realized on steep paths (mountain, desert…) with an important variation of elevation. Neuromuscular, biomechanical and physiological consequences are different depending on the discipline, especially with a greater eccentric contribution in trail running. In spite of this characteristic, trail runners take part in several races longer than 40 km per year, while road runners participate in one to two marathons per year.
Who can participate
Age range
18 Years – 55 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
Common for MARASIM, TRAILSIM and TRAILNAT:
* Male or female
* 18-55 years old
* Endurance runners who run at least one running session of 20 km per week
* Being able to run a marathon under 5 h or finishing a trail of 30 km during the last 3 years
* Refrain from participating to a competition one month before the first visit and during the duration of the study
* To have a medical certificate of no contraindication of running practise in competition
* Registered with a social security scheme
* Having given the written consent freely
Specific for the 3 groups :
* Specialist of trail running (TRAILSIM and TRAILNAT)
* Specialist of road running (MARASIM)
Exclusion Criteria:
* Subjects who present cardiac or articular chronic pathologies (example: repeated sprain, patellar or joint problems)
* Subjects who present chronic or central neurological pathologies
* Subjects deprived of liberty or who should be legally deprived
* Subjects who report to take forbidden products by the World Anti-Doping Agency
* pregnant or breastfeeding woman
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Change in knee extensors maximal isometric torque output
Timeframe: Day 0 (day of the race) baseline value = 30 minutes before the race and 15 minutes after the race
Trial details
NCT IDNCT06282341
SponsorCentre Hospitalier Universitaire de Saint Etienne