RecruitingNot Applicable

PRP Versus PRF Versus Conventional Treatment in Chronic Non-healing Skin Ulcers

Egypt36 participantsStarted 2024-01-01

Plain-language summary

To compare the therapeutic efficacy of PRP and PRF: two relatively newer modalities in the management of chronic non-healing ulcers versus conventional treatment.

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients presenting with cutaneous ulcers greater than six weeks of duration and a size ranging between 0.5 and 10 cm, having a normal platelet count and hemoglobin \>10 gm%. Exclusion Criteria: * Patients with known bleeding disorders, and/or on oral anticoagulant therapy, uncontrolled diabetes, proven malignancy. * Patients who are pregnant or lactating. * Patients with actively infected ulcers, clinically defined by purulent discharge, green discoloration or fever, or positive culture, ulcers with exposed bone with no underlying granulation tissue, HIV, HCV, HBV patients. * Patients who are with unrealistic expectations and unwilling to give consent for treatment or photography.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Objective assessment of ulcer size for effectiveness, using Image J software.

Timeframe: Four months of follow up after eight sessions of treatment (six months total)

Pain assessment

Timeframe: Four months of follow up after eight sessions of treatment (six months total)

Any adverse effects related to treatment modality

Timeframe: Four months of follow up after eight sessions of treatment (six months total)

Trial details

NCT IDNCT06281483

SponsorKafrelsheikh University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-01-01

Contact for this trial

Mohamed Aboshabana Hussein, Assistant Lecturer

01007981008 dr.mohamedaboshabana@gmail.com

View on ClinicalTrials.gov More Chronic Non-healing Skin Ulcers trials

Who can participate

Age range

18 Years – 65 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Objective assessment of ulcer size for effectiveness, using Image J software.

Timeframe: Four months of follow up after eight sessions of treatment (six months total)

Pain assessment

Timeframe: Four months of follow up after eight sessions of treatment (six months total)

Any adverse effects related to treatment modality

Timeframe: Four months of follow up after eight sessions of treatment (six months total)