LBNP Tolerance With Skin Warming After Exercise Cold Stress (NCT06279897) | Clinical Trial Compass
Active — Not RecruitingNot Applicable
LBNP Tolerance With Skin Warming After Exercise Cold Stress
United States10 participantsStarted 2022-01-24
Plain-language summary
Assess the effect of skin rewarming during lower body negative pressure upon arterial blood pressure and tolerance to simulated blood loss after exercise in the cold.
Who can participate
Age range
18 Years – 40 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 and 40 years old
* free of known disease and illness
* Speak English
* Systolic blood pressure \<140mmHg
* Diastolic blood pressure \<90 mmHg
Exclusion Criteria:
* Currently pregnant or breast feeding
* Individuals with diagnosed with cardiac, respiratory, neurological and/or metabolic illness or disease.
* Currently taking prescribed or over the counter medications known to influence the cardiovascular, pulmonary, renal and/or central nervous system.
* Current use of tobacco or nicotine products
* Any physical limitations that impede completion of the tests, such as exercise tests will also be an exclusion criteria.
* Body mass\< 80 pounds body weight
* Appendectomy
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Arterial blood pressure
Timeframe: Before and during lower body negative pressure (LBNP) procedure
2
Tolerance to simulated blood loss
Timeframe: Lower body negative pressure test duration in all trials.