Active — Not RecruitingNot Applicable

LBNP Tolerance With Skin Warming After Exercise Cold Stress

United States10 participantsStarted 2022-01-24

Plain-language summary

Assess the effect of skin rewarming during lower body negative pressure upon arterial blood pressure and tolerance to simulated blood loss after exercise in the cold.

Who can participate

Age range18 Years – 40 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18 and 40 years old * free of known disease and illness * Speak English * Systolic blood pressure \<140mmHg * Diastolic blood pressure \<90 mmHg Exclusion Criteria: * Currently pregnant or breast feeding * Individuals with diagnosed with cardiac, respiratory, neurological and/or metabolic illness or disease. * Currently taking prescribed or over the counter medications known to influence the cardiovascular, pulmonary, renal and/or central nervous system. * Current use of tobacco or nicotine products * Any physical limitations that impede completion of the tests, such as exercise tests will also be an exclusion criteria. * Body mass\< 80 pounds body weight * Appendectomy

What they're measuring

Arterial blood pressure

Timeframe: Before and during lower body negative pressure (LBNP) procedure

Tolerance to simulated blood loss

Timeframe: Lower body negative pressure test duration in all trials.

Trial details

NCT IDNCT06279897

SponsorUniversity of Colorado, Colorado Springs

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-09-30

View on ClinicalTrials.gov More Blood Pressure trials