CompletedPhase 3

Vitamin D & Levothyroxine Combination Versus Levothyroxine on Lipid Profile in Hypothyroidism

Pakistan62 participantsStarted 2024-03-01

Plain-language summary

The goal of this clinical trial is to study the improvement of lipid levels in hypothyroid individuals after staring treatment. The main question it aims to answer is: • whether adding Vitamin D to standard therapy has any additional benefits Participants will be given Vitamin D in replacement doses according to their pre-existing Vitamin D level in addition to levothyroxine. Researchers will compare them with another group receiving only levothyroxine to see how much lipids improve in them

Who can participate

Age range12 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients of all genders. * Age more than 12 years * Biochemically hypothyroid (overt \& subclinical) * Vitamin D level between 10-70ng/ml * TC \<250mg/dl, LDL 70-144mg/dl, TGs 150-499mg/dl Exclusion Criteria: * Known Atherosclerotic Cardiovascular Disease * BMI\>35kg/m2 * History of Alcoholism (\>14 units/day) * History of Beta blocker intake * Patient taking lipid lowering drugs

What they're measuring

Decline in Total Cholesterol

Timeframe: 24 weeks

Decline in LDL

Timeframe: 24 weeks

Trial details

NCT IDNCT06276205

SponsorKing Edward Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-01

View on ClinicalTrials.gov More Hypothyroidism Primary trials