CompletedNot Applicable

Project Phakama: Testing Support Strategies to Empower Young Women on PrEP in South Africa

South Africa304 participantsStarted 2024-04-16

Plain-language summary

The goal of this trial is to understand which strategies work best to support pre-exposure prophylaxis (PrEP) use among female sex workers (FSW) and adolescent girls and youth women (AGYW) in uMgungundlovu, KwaZulu-Natal, South Africa. Participants will be randomly assigned to receive a combination of up to four support strategies encourage the participants in continuing to use PrEP. The four strategies being tested are: case management, food vouchers, peer support buddies, and community-based PrEP pick-up points. The intention of this trial is to determine which PrEP support strategy or bundle(s) of strategies best promote(s) long-term PrEP use, so that these services can be scaled up to other districts in South Africa.

Who can participate

Age range16 Years

SexFEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Initiated PrEP within the past 48 hours by the TB HIV Care PrEP programme in uMgungundlovu through the female sex worker (FSW) or adolescent girls and young women (AGYW) PrEP programme teams Exclusion Criteria: * Not eligible for PrEP * Currently on PrEP, but initiated onto PrEP more than 48 hours previously * Under 16 years of age if AGYW OR under 18 years of age if FSW

What they're measuring

PrEP persistence at 7 months after PrEP initiation

Timeframe: Month 7

PrEP adherence at 7 months after PrEP initiation among all trial participants

Timeframe: Month 7

Trial details

NCT IDNCT06274060

SponsorJohns Hopkins Bloomberg School of Public Health

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-06-01

View on ClinicalTrials.gov More Pre-exposure Prophylaxis trials