UnknownNot Applicable

Comparison of the Effect of Aminophylline, Magnesium Sulphate and Placebo in Prevention of Post Dural Puncture Headache in Parturient Undergoing Caesarean Section.

630 participantsStarted 2024-03

Plain-language summary

This study will be conducted to better comprehend the effect of aminophylline in comparison to magnesium sulphate on preventing and/or treating PDPH.

Who can participate

Age range

18 Years – 35 Years

Sex

FEMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * All parturient who underwent cesarean section under spinal anesthesia. * Patients who are willing to participate in the trial gave an informed consent. * ASA physical status II. * The age ranged from 20 to 40. * Body Mass Index (BMI) ranged from 25 to 30 kg/m2. Exclusion Criteria: * Patient refusal. * Allergy to the studied drugs. * Patients with contraindications to spinal anesthesia. * Those with past history of chronic headache or recent onset of acute headache were excluded. * Women who had multiple punctures (\>2) during the spinal anesthesia procedure were excluded from the study. * Patients with advanced decompensated cardiac, renal, hepatic disease.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Effect of the study drugs on the incidence and severity of PDPH

Timeframe: 100ml of the prepared study drug intravenously immediately after the baby was delivered and umbilical cord was clamped.

Trial details

NCT IDNCT06272916

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2025-04

Contact for this trial

Reham M. Abdelbary

01063211106 rehammohamed1304@gmail.com

View on ClinicalTrials.gov More Post-Dural Puncture Headache trials