CompletedPhase 3

Pregabalin in Treatment of Postdural Puncture Headache

Egypt75 participantsStarted 2024-02-28

Plain-language summary

Lumbar puncture (LP), often known as a "spinal tap," is a standard medical technique pioneered in the late 1900s by Heinrich Quincke. It involves the retrieval and analysis of cerebrospinal fluid (CSF) from the spinal cord, serving as the benchmark for diagnosing conditions like subarachnoid hemorrhage, meningitis, and specific neurological conditions. Pregabalin, an anticonvulsant medicine that blocks calcium entry, is used to treat a variety of diseases. It has been used to relieve pain in a variety of patient groups, including those with chronic pain, epilepsy, and anxiety disorders

Who can participate

Age range21 Years – 65 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * age from 21 to 65 years old, * both genders, * confirmed diagnosis of postdural puncture headache (PDPH) Exclusion Criteria: * patient refusal * known allergy to the drug used in the study * patients with a history of convulsions * chronic headaches * contraindications to regional anesthesia (such as local infection and coagulation abnormalities). * Clinical indications of elevated intracranial pressure or associated risk factors * Deteriorated patients

What they're measuring

the incidence of complete relief

Timeframe: 48 hours

Trial details

NCT IDNCT06271486

SponsorAl-Azhar University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-08-15

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