Evaluation of the Effects of Routine Intake of Fresh vs- Pasteurized Yoghurt on the Immune System… (NCT06263686) | Clinical Trial Compass
CompletedNot Applicable
Evaluation of the Effects of Routine Intake of Fresh vs- Pasteurized Yoghurt on the Immune System in Healthy Adults
125 participantsStarted 2016-06-01
Plain-language summary
In this study, the purpose was to describe and compare the modulator effects on the immune system of the routine ingestion of fresh vs. pasteurized yoghurt. A unicentral, prospective, randomized, double-blind, parallel group nutritional study for 8 weeks was carried out comparing the ingestion of 125 g (three times a day) of the products in healthy adults. A complete battery of in vitro tests on the activity of immune system, processes and phenomena was performed.
Who can participate
Age range20 Years – 70 Years
SexALL
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Inclusion criteria
* Age between 20 and 70 years, both included.
* Healthy or mildly ill subjects (without any current chronic pharmacotherapy).
* Body mass index between 18.5 and 29.9 kg/m2, both included.
* Subjects who usually follow a balanced diet that are not engaged in any therapeutic lifestyle change involving stringent dietary interventions such as weight-reducing diets.
* Written informed consent to participate
Exclusion criteria
* Patients could not meet any the following criteria at the screening visit to be included in the study.
* Subjects with diseases or disorders affecting the function of the immune system, such as auto-immune diseases, allergies, atopic conditions, hypersensitivity to any kind of stimulus, or immunosupression for any reason; even if they are not currently taken any pharmacotherapy.
* Subjects with relevant functional or structural disorder affecting the gastrointestinal tract, such as malformations, angiodysplasias, active peptic ulcers or chronic inflammatory disease of the intestine; even if they are not in any specific pharmacotherapy at the time of recruitment; or who have underwent surgical procedures with permanent sequels (for example, gastroenterostomy).
* Subjects with any infectious disease requiring antibiotherapy at the time of recruitment.
* Subjects following any treatment modifying the immune response, such as immunosuppressants, corticosteroids, etc.
* Subjects with celiac disease.
* Subjects with chronic background weaken…