Sleep Profile of Patients With Septo-optic Dysplasia

Inclusion criteria group A: * diagnosis of SOD or SOD plus syndrome with or without a defined genetic diagnosis * age 3-18 years * availability of at least 2 serial sleep EEGs performed during clinical follow-up * stable drug therapy in the last three months Inclusion criteria group B: * diagnosis of congenital or early acquired isolated peripheral visual deficit with or without a known genetic diagnosis (e.g., congenital cataract, inherited retinal dystrophies, isolated eye maldevelopment). * age 3-18 years * grating or visual acuity \< 3/10 * availability of serial sleep EEGs performed during clinical follow-up * stable drug therapy in the last three months Inclusion criteria group C * isolated corpus callosum agenesis at brain MRI * age 3-18 years * availability of at least 2 serial sleep EEGs performed during clinical follow-up * stable drug therapy in the last three months Exclusion criteria group A: * absence of informed consent * severe Intellectual disability and/or severe motor impairment * melatonin assumption Exclusion criteria group B: * absence of informed consent * CNS involvement ( malformations/ lesions) * severe Intellectual disability and/or severe motor impairment * melatonin assumption Exclusion criteria group C * absence of informed consent * severe Intellectual disability and/or severe motor impairment * melatonin assumption