Effect of Gabapentin on Kidney Function Following Laparoscopic Sleeve Gastrectomy(LSG)

Inclusion Criteria: * Morbid obese patients with normal kidney function, undergoing Laparoscopic sleeve gastrectomy surgery. * Both sexes. * Age ≥ 18 years Exclusion Criteria: * • Patients have advanced cancer on active treatment and end-stage renal, hepatic, and cardiopulmonary disease. * Patients with untreated schizophrenia, cognitive impairment and using psychiatric medications. * Patients with active substance abuse. * Patients on chronic dosage of Gabapentin or allergic to it. * Pregnant women or women on breastfeeding. * Patients on medications that could interfere with assessed parameters will be excluded. The ethical approval of the study will be obtained from by Medical research Ethics Committee of Tanta and Mansoura Universities and all participants will give their written consent.