Lower Placental Edge Thickness in Relation to Gestational Age at Delivery in Placenta Accreta (Pr… (NCT06248385) | Clinical Trial Compass
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Lower Placental Edge Thickness in Relation to Gestational Age at Delivery in Placenta Accreta (Prospective Cohort Study)
Egypt50 participantsStarted 2024-02-12
Plain-language summary
The aim of our study is to determine correlation between lower placental edge thickness measured by ultrasound and gestational age at delivery and predict the risk of emergency preterm birth in patients having placenta previa accreta.
Who can participate
Age range18 Years – 45 Years
SexFEMALE
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Inclusion Criteria:
Single, viable gestations. Gestational age \>28 weeks, \< 36 weeks.
Confirmed diagnosis of placenta previa accreta when the placenta lies directly over the internal os based on ultrasound features among RCOG criteria as follows) RCOG,2019):
2D greyscale signs: loss of myometrial interface or retroplacental clear space, reduced myometrial thickness, intra-placental blood flow and intra-placental lacunae.
2D color Doppler signs: intra-placental blood flow, the presence of altered blood flow in the retroplacental space and aberrant vessels crossing between placental surfaces.
First time of diagnosis of placenta previa accreta is 28-30 weeks. Previous one or more cesarean sections.
Exclusion Criteria:
Maternal medical co-morbidities like diabetes and hypertension. Patients with bleeding disorders or anticoagulant therapy. Over distended uterus e.g.: multiple gestation, polyhydramnios, fetal macrosomia(\>4.5kg).
Fetal anomalies or fetal growth restriction. Emergency cesarean section due to fetal distress. Rupture of membranes, intra-amniotic infection and fever during admission (\>38 °C).
History of cervical cerclage or cervical cone biopsy.
What they're measuring
1
Lower placental edge thickness measurements by ultrasound in patients having placenta previa accreta.