A Phase 2a Study To Evaluate VMB-100 In Females With Stress Urinary Incontinence

Main inclusion criteria: * Pre- or peri-menopausal female subject between 18 and 55 years of age * Body mass index (BMI) of 19 to 35 kg/m2 * Active SUI of moderate severity for at least 6 consecutive months documented in medical history * Refractory to standard of care measures * Must not be pregnant, lactating, or actively trying to become pregnant. Main exclusion criteria: * Any concurrent condition or any clinically significant abnormality at Screening which in the opinion of the Investigator may affect the interpretation of safety or efficacy data or which otherwise contradicts participation in a clinical study with VMB-100 * Unwilling to undergo transvaginal sonography or cystoscopy * Urodynamic detrusor overactivity * History of urinary urge incontinence of neurogenic etiology. * History of or planning for pelvic radiation. * History of use of any bulking agent or Botox to treat SUI in the past 12 month. * History of urethral sling, anterior prolapse repair, and/or other SUI procedures or surgical procedures affecting continence. * Taking any medications that are known to have an effect on urinary continence or medications that may exacerbate incontinence