Chondro-Long study is prospective observational study for a long-term clinical evaluation (follow-up up to 25 years) in patients treated with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) at the level of femoral condyles, trochlea, patella and tibial plateau. The aim of the study is to collect long-term clinical data from the case series of patients surgically treated from 1999 to 2006 with autologous chondrocyte transplantation delivered on biomaterial for full-thickness chondral defects (Outerbridge grade III - IV) or osteochondral defects at the level of femoral condyles, trochlea, patella, and tibial plateau. The objective of the study is to demonstrate the efficacy of this long-term cartilage regeneration technique (follow-up up to 25 years) in improving patient symptomatology and functional capacity
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Knee Injury and Osteoarthritis Outcome Score (IKDC)-Subjective Knee Evaluation Form
Timeframe: baseline
EuroQol Visual Analogue Scale (EQ-VAS )
Timeframe: baseline
Tegner Score
Timeframe: baseline
EQ-5D (EuroQoL) Current Health Assessment
Timeframe: baseline
MCD/MCID (Minimal Clinically Important Difference):
Timeframe: baseline
Patient Acceptable Symptom State (PASS)
Timeframe: baseline