Low Dose Ketamine for Blunt Thoracic Trauma

Inclusion Criteria: * Males or females 18 years of age or older * Diagnosis of 3 or more acute rib fractures related to blunt traumatic chest injury. * Able to undergo consent procedure and give valid consent, or availability of family member to provide consent for the study Exclusion Criteria: * Age \<18 years * Cognitively impaired * Pregnant or lactating females. * Glasgow Coma Score (GCS) of ≤ 14 at time of admission * Evidence of increased intraocular pressure * Presence of acute coronary syndrome * Diagnosed moderate to severe traumatic brain injury * Evidence of uncontrolled intracranial hypertension * History of seizures or stroke * History of severe psychiatric disorders * Allergy to ketamine * Currently being treated, prior to admission, with opiate agonist/antagonist therapy * Presence of poorly controlled hypertension, cardiac arrhythmias, and/or tachycardia on admission * Subjects who, in the opinion of the Investigator, may be inappropriate for study participation.