A Study of Amantadine for Cognitive Dysfunction in Patients With Long-Covid

Inclusion Criteria: * Age 20-65 * Can provide informed consent * Confirmed COVID+ test (either rapid antigen or PCR) between 8 weeks and one year prior to initial visit. * Able to consent in English * Endorse symptoms during their initial evaluation and history with the provider that began around the time of the acute COVID19 infection (subjective) including cognitive changes such as cognitive fatigue, brain fog, memory issues,attention issues AND have symptoms in at least 1 out of the 2 following symptom categories: * Category 1: Decreased endurance, physical fatigue, weakness * Category 2: Depression, anxiety Exclusion Criteria: * Known hypersensitivity to amantadine * Clinically significant psychiatric, neurologic, renal, hepatic, opthalmologic, cardiac impairment in the opinion of the investigators, including but not limited to: * Psychiatric: * Acute or chronic unstable Axis I psychiatric illness * History of psychosis * Severe depression Patient Health Questionnaire-9 (PHQ-9) score \>= 20 * Suicidality * Neurologic: * Epilepsy * Cognitive dysfunction predating COVID infection * History of delirium * Neurologic conditions with agitation or confusion