Juvenile systemic lupus erythematosus is an autoimmune disorder with multisystem involvement, leading to inflammatory damage to the joints, kidney, central nervous system, and hematopoietic system. Although the prevalence rate of juvenile systemic lupus erythematosus in a developing country is not known, as per literature the female-to-male ratio rises from 4.5 : 1 in adolescence to 8--12 : 1 in adult-onset patients. \- The full mechanism of SLE is still unknown however, production of autoantibodies and immune complex deposition with subsequent infiltration of neutrophils, hyper-activation of B and T cells, reduced ability of immune complexes and apoptotic cell clearance, and defects in multiple immune regulatory networks, are central to organ inflammation and subsequent damage in SLE. Systemic lupus erythematosus goes on with organ involvements by remission and relapses.
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Measure the absolute neutrophil-to-absolute lymphocyte ratio (NLR).
Timeframe: Baseline
Measure the mean platelet volume (MPV).
Timeframe: Baseline
Measure the platelet count-to-absolute lymphocytes ratio (PLR).
Timeframe: Baseline
Measuring the monocyte distribution width (MDW)}.
Timeframe: Baseline